Atherosclerosis and hypercholesterolemia



A condition characterized by high cholesterol accumulation in the body.

itself is asymptomatic, longstanding elevation of serum cholesterol can lead to atherosclerosis (hardening of arteries). Over a period of decades, elevated serum cholesterol contributes to formation of atheromatous plaques in the arteries. This can lead to progressive narrowing of the involved arteries.Other names: Specialty: 

What is atherosclerosis and cholesterol?

Atherosclerosis and cholesterol. When plaque (fatty deposits) clogs your arteries, that’s called atherosclerosis. These deposits are made up of cholesterol, fatty substances, cellular waste products, calcium and fibrin (a clotting material in the blood). As plaque builds up, the wall of the blood vessel thickens.

What is atherosclerosis and how does it develop?

Development of atherosclerosis. Development of atherosclerosis Atherosclerosis is a process in which blood fats such as cholesterol and other substances build up on your artery walls. Eventually, deposits called plaques may form. The deposits may narrow, or block, your arteries.

How to reduce atherosclerosis?

Both medications and changes in lifestyle can improve cholesterol level and reduce the risks that come with atherosclerosis: Exercise with or without weight loss increases “good” HDL cholesterol and reduces the risk of heart attacks and strokes. A diet high in fiber and low in fats can lower “bad” LDL cholesterol.

Is atherosclerosis high oxidative stress?

Currently, the idea that atherosclerosis constitutes a state of high levels of oxidative stress is widely accepted and this phenomenon is associated with lipid and protein oxidation in the vascular wall [ 3, 4 ].

Can I reverse atherosclerosis?

It’s clear that atherosclerosis can be reversed through exercise, diet changes, smoking cessation, and stress reduction.

Is reversing atherosclerosis possible?

Atherosclerosis thus leads to restricted blood flow. Limited supply of blood and oxygen to the brain, heart and other organs can affect their functions badly. Reversing atherosclerosis is possible by undergoing a surgery or it is possible if a balanced diet is followed and exercises are performed regularly.

What causes atherosclerosis calcification?

Atherosclerosis, sometimes called “hardening of the arteries,” occurs when fat (cholesterol) and calcium build up in the wall of the arteries, forming a substance called plaque. Over time, the fat and calcium buildup may narrow the artery and reduce blood flow through it.

Can statins actually reverse plaque buildup?

Statins May Reverse Plaque Buildup . “But what we found is that if you lower LDL cholesterol to very low levels and keep it there for two years, you can remove plaque in fairly significant quantities and partially reverse coronary artery disease ,” he tells WebMD.