Can stem cells cure sickle cell anemia

The deformed cells can block blood flow, causing severe pain, organ damage, and stroke. There is no widely available cure for sickle cell disease. Some children with the disease have been successfully treated with blood stem cell, or bone marrow, transplants. This approach, though, was thought to be too toxic for use in adults.

What are the effects of sickle cell anemia?

Sickle cell anemia leads to pain in the bones. It can also lead to shortness of breath, fatigue, chest pain, strokes. It affects the bones, brain, kidneys, heart, joints, lungs and spleen.

Can you die of sickle cell anemia?

Sickle cell anemia may lead to ACS which may lead to death. Until recently, all those who had sickle-cell anemia could live up to 14 years only on an average. But currently, the life expectancy has increased to 50 years and sometimes more. Women generally live longer than men with sickle cell anemia.

How does sickle cell anemia affect life expectancy?

The life expectancy of people suffering from sickle cell anaemia is reduced. Some patients might survive for years, while others may not even survive infancy. Sickle cell anaemia is a genetic disorder. Both parents must be carriers of sickle cell anaemia for the child to be affected by this disease.

How does a person get sickle cell anemia?

Sickle cell anemia is an inherited disease caused by a genetic mutation. A person who receives the defective gene from both their father and mother develops the disease; a person who receives one defective gene and a healthy one, will not have the disease but will be a carrier of the sickle cell trait.

What are people most likely to develop sickle cell anemia?

Sickle cell disease is more common in certain ethnic groups, including: People of African descent , including African-Americans (among whom 1 in 12 carries a sickle cell gene) Hispanic-Americans from Central and South America. People of Middle Eastern, Asian, Indian, and Mediterranean descent.

How does sickle cell anemia affect life expectancy?

The life expectancy of people suffering from sickle cell anaemia is reduced. Some patients might survive for years, while others may not even survive infancy. Sickle cell anaemia is a genetic disorder. Both parents must be carriers of sickle cell anaemia for the child to be affected by this disease.

How does sickle cell anaemia affect the body?

Sickle cell anemia causes an oxygen deficiency in different parts of the body, which can be dangerous. For instance, if developing cells do not receive enough oxygen, their growth can be stunted. Often, a person with sickle cell anemia will have a low amount of red blood cells because sickle cells are abnormally frail, which can cause anemia.

How can sickle cell kill a person?

Sickle cell can also cause stroke. It damages many organs (impairing the kidney’s ability to concentrate urine; infarcting (death from low oxygen/blood flow) areas of bone marrow, etc–it’s how the spleen is lost too). When this happens in the brain you get permanent neurologic damage (mild to severe).