Is double hit lymphoma curable

The prognosis of Double Hit Lymphoma depends on many factors including the subtype and stage of lymphoma, progression of the condition, response to treatment, and overall health of the individual. However, typically the prognosis of DHL is poor.

What is the survival rate for double hit lymphoma?

All the double-hit lymphoma patients possessed both nodal and extranodal involvement. The overall complete response rate was 89.3%, overall survival 87.1% and progression-free survival 75.8% over 2 years (median observation period: 644 days).

What is the prognosis for double hit lymphoma?

The prognosis of Double Hit Lymphoma depends on many factors including the subtype and stage of lymphoma, progression of the condition, response to treatment, and overall health of the individual. However, typically the prognosis of DHL is poor.

What is treatment for triple hit lymphoma?

If Triple Hit Lymphoma is not fully responsive to treatment, or if the chance of recurrence is high, then bone marrow transplantation or stem cell transplantation can be considered In order to prevent infections because the immune system is weakened by the lymphoma or by its treatment,…

What is double hit B cell lymphoma?

Double Hit-Lymphoma. Similar to Burkitt lymphoma, “double hit” lymphoma is a diffuse large B cell lymphoma with both a c-myc translocation and a bcl-2 translocation. These activating mutations drive proliferation and prevent apoptosis (programmed cell death), respectively.

What is the prognosis for double hit lymphoma?

The prognosis of Double Hit Lymphoma depends on many factors including the subtype and stage of lymphoma, progression of the condition, response to treatment, and overall health of the individual. However, typically the prognosis of DHL is poor.

How do I treat “double hit” lymphoma?

Relapsed Double-Hit Lymphoma. The standard curative approach to the treatment of relapsed aggressive lymphoma in fit patients is to administer non-cross-resistant salvage chemotherapy followed by consolidation with high-dose therapy and AHCT, but outcomes in patients with MYC-rearranged disease are poor.

What is treatment for triple hit lymphoma?

If Triple Hit Lymphoma is not fully responsive to treatment, or if the chance of recurrence is high, then bone marrow transplantation or stem cell transplantation can be considered In order to prevent infections because the immune system is weakened by the lymphoma or by its treatment,…

What is triple hit B cell lymphoma?

Triple Hit Lymphoma (THL) is a highly uncommon and aggressive B-cell non-Hodgkin lymphoma. It generally affects elderly adults. The lymphoma is called ‘triple hit’, because unlike a vast majority of lymphomas that have a single genetic mutation, THL has 3 mutations.